3D Object Tracking and Lineage Tracing
Capturing the motion of life
Detecting, analyzing and understanding how cells, organelles and particles move in 3D environments is essential for a wide range of research fields. Moreover, normal cell division and cell differentiation are both critical to the development and homeostasis of most biological systems including humans. Abnormal cell division and uncontrolled cell differentiation are critical factors in a variety of conditions including cancer, immunological disorders and developmental defects.
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Aivia 7 introduces a state-of-the-art 3D object tracking approach which builds on the 3D object detection recipe launched in Aivia 6 and seamlessly blends the advantages of motion and intensity based object tracking. See our ASCB|EMBO 2017 poster describing underlying technology here.
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In addition, Aivia 7 automatically traces cell lineages and displays them in the 3D View and in two plot types (Lineage and Flow plot). Both plots are synchronized with the 3D View, the Track Editor (see below) as well as the Spreadsheet thus allowing the user to easy inspection of the results, determine their accuracy as well as relevance.
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3D object tracking
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3D lineage tracing and fate analysis
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Dual score tracking algorithm (Motion vs Intensity)
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Wide range of track display options
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Motion and lineage specific measurements
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Supports large data sets (tens of GB per time point, over 1TB per experiment)
After tracking the user has a myriad of track display options which include independent controls for tracks, anchors (i.e. the track points), trends (i.e. the vectors that indicate overall direction for each track). Each display option has its own size/scale and color controls to ensure you can get the perfect visualization output for your presentations and publications.
Note: Aivia introduced 2D object tracking and lineage tracing in 2013
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Track and Lineage Editing
As easy as drag-and-drop
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Connect and disconnect tracks
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Use Workspaces to conveniently edit groups of tracks
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Create and edit lineages
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Multiple and easy track selection options
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Review edits in real time
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Synchronization between data view, Track Editor, Charts and Spreadsheet
Aivia 7 offers you a complete and highly intuitive Track Editor so you can build on the results automatically generated. This way you have the option to get to the perfect result by leveraging your trained eye.
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The editor allows you to create multiple Workspaces where you can interact with and edit a subset of tracks/lineages without being distracted by all the items you are not interested in editing. Making an edit consists of a single click-drag-n-drop. Aivia will ask you what kind of edit you want to do before completing it. The edits automatically update the 3D View, the Spreadsheet, the Charts and all the Track Editor Workspaces. The track editor supports undo/redo - sometimes a big time saver.
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